Treatment of secondary lymphedema of the upper limb with cyclo 3 fort
Identifieur interne : 000924 ( France/Analysis ); précédent : 000923; suivant : 000925Treatment of secondary lymphedema of the upper limb with cyclo 3 fort
Auteurs : R. V. Cluzan [France] ; F. Alliot [France] ; S. Ghabboun [France] ; M. Pascot [France]Source :
- Lymphology [ 0024-7766 ] ; 1996.
Descripteurs français
- KwdFr :
- Adulte, Bras (anatomopathologie), Calendrier d'administration des médicaments, Drainage (), Extraits de plantes (usage thérapeutique), Facteurs temps, Femelle, Humains, Lymphoedème (diagnostic), Lymphoedème (traitement médicamenteux), Lymphoedème (étiologie), Méthode en double aveugle, Tumeurs du sein (), Vasodilatateurs (usage thérapeutique).
- MESH :
- anatomopathologie : Bras.
- diagnostic : Lymphoedème.
- traitement médicamenteux : Lymphoedème.
- usage thérapeutique : Extraits de plantes, Vasodilatateurs.
- étiologie : Lymphoedème.
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Adult, Arm (pathology), Breast Neoplasms (therapy), Chemotherapy, Comparative study, Double-Blind Method, Drainage (methods), Drug Administration Schedule, Exploration, Female, Flavonoid, Hesperidin, Human, Humans, Lymphedema, Lymphedema (diagnosis), Lymphedema (drug therapy), Lymphedema (etiology), Plant Extracts (therapeutic use), Secondary, Time Factors, Treatment, Upper limb, Vasodilator Agents (therapeutic use), Venotropic agent.
- MESH :
- chemical , therapeutic use : Plant Extracts, Vasodilator Agents.
- diagnosis : Lymphedema.
- drug therapy : Lymphedema.
- etiology : Lymphedema.
- methods : Drainage.
- pathology : Arm.
- therapy : Breast Neoplasms.
- Adult, Double-Blind Method, Drug Administration Schedule, Female, Humans, Time Factors.
Abstract
Fifty seven patients with secondary lymphedema of the upper limb after previous treatment for breast cancer were treated for 3 months with an extract of Ruscus + Hesperidin Methyl Chalcone (CYCLO 3 FORT) or placebo according to a double-blind protocol in the context of a controlled clinical trial. All patients also underwent manual lymphatic drainage twice a week for at least one month. With CYCLO 3 FORT, the reduction in volume of arm edema, the main assessment criteria, was 12.9% after 3 months of treatment as compared with a placebo (p=0.009). Decreased edema tended to be more marked in the forearm compared with the upper arm where excess fat deposition seemed to dominate over excess fluid accumulation. CYCLO 3 FORT was well tolerated with minimal adverse reaction.
Affiliations:
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Pascal:96-0216041Le document en format XML
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V." last="Cluzan">R. V. Cluzan</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Unité de Lymphologie, Hôpital Cognacq-Jay</s1><s2>Paris</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Alliot, F" sort="Alliot, F" uniqKey="Alliot F" first="F." last="Alliot">F. Alliot</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Unité de Lymphologie, Hôpital Cognacq-Jay</s1><s2>Paris</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Ghabboun, S" sort="Ghabboun, S" uniqKey="Ghabboun S" first="S." last="Ghabboun">S. Ghabboun</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Unité de Lymphologie, Hôpital Cognacq-Jay</s1><s2>Paris</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Pascot, M" sort="Pascot, M" uniqKey="Pascot M" first="M." last="Pascot">M. Pascot</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Unité de Lymphologie, Hôpital Cognacq-Jay</s1><s2>Paris</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Lymphology</title><title level="j" type="abbreviated">Lymphology</title><idno type="ISSN">0024-7766</idno><imprint><date when="1996">1996</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Lymphology</title><title level="j" type="abbreviated">Lymphology</title><idno type="ISSN">0024-7766</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Arm (pathology)</term><term>Breast Neoplasms (therapy)</term><term>Chemotherapy</term><term>Comparative study</term><term>Double-Blind Method</term><term>Drainage (methods)</term><term>Drug Administration Schedule</term><term>Exploration</term><term>Female</term><term>Flavonoid</term><term>Hesperidin</term><term>Human</term><term>Humans</term><term>Lymphedema</term><term>Lymphedema (diagnosis)</term><term>Lymphedema (drug therapy)</term><term>Lymphedema (etiology)</term><term>Plant Extracts (therapeutic use)</term><term>Secondary</term><term>Time Factors</term><term>Treatment</term><term>Upper limb</term><term>Vasodilator Agents (therapeutic use)</term><term>Venotropic agent</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Bras (anatomopathologie)</term><term>Calendrier d'administration des médicaments</term><term>Drainage ()</term><term>Extraits de plantes (usage thérapeutique)</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lymphoedème (diagnostic)</term><term>Lymphoedème (traitement médicamenteux)</term><term>Lymphoedème (étiologie)</term><term>Méthode en double aveugle</term><term>Tumeurs du sein ()</term><term>Vasodilatateurs (usage thérapeutique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Plant Extracts</term><term>Vasodilator Agents</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Bras</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Drainage</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Arm</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Extraits de plantes</term><term>Vasodilatateurs</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Double-Blind Method</term><term>Drug Administration Schedule</term><term>Female</term><term>Humans</term><term>Time Factors</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term><term>Calendrier d'administration des médicaments</term><term>Drainage</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lymphoedème</term><term>Membre supérieur</term><term>Méthode en double aveugle</term><term>Secondaire</term><term>Hespéridine</term><term>Chimiothérapie</term><term>Traitement</term><term>Exploration</term><term>Homme</term><term>Etude comparative</term><term>Flavonoïde</term><term>Tumeurs du sein</term><term>Veinotrope</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Fifty seven patients with secondary lymphedema of the upper limb after previous treatment for breast cancer were treated for 3 months with an extract of Ruscus + Hesperidin Methyl Chalcone (CYCLO 3 FORT) or placebo according to a double-blind protocol in the context of a controlled clinical trial. All patients also underwent manual lymphatic drainage twice a week for at least one month. With CYCLO 3 FORT, the reduction in volume of arm edema, the main assessment criteria, was 12.9% after 3 months of treatment as compared with a placebo (p=0.009). Decreased edema tended to be more marked in the forearm compared with the upper arm where excess fat deposition seemed to dominate over excess fluid accumulation. CYCLO 3 FORT was well tolerated with minimal adverse reaction.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Cluzan, R V" sort="Cluzan, R V" uniqKey="Cluzan R" first="R. V." last="Cluzan">R. V. Cluzan</name></region><name sortKey="Alliot, F" sort="Alliot, F" uniqKey="Alliot F" first="F." last="Alliot">F. Alliot</name><name sortKey="Ghabboun, S" sort="Ghabboun, S" uniqKey="Ghabboun S" first="S." last="Ghabboun">S. Ghabboun</name><name sortKey="Pascot, M" sort="Pascot, M" uniqKey="Pascot M" first="M." last="Pascot">M. Pascot</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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